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The compounded formulation is prepared by licensed U.S.-based pharmacies that follow federal and state compounding guidelines

Chronic 16-day administration resulted in an average 8.6% decrease in body weight relative to baseline, with a 13.8% relative weight loss compared to vehicle controls

It also suggests that anyone with moderate-to-severe nausea in the first two to four weeks trial removing caffeine before assuming the medication itself is the cause of the symptoms