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Peeters F, Cassiman C, Van Keer K, Levtchenko E, Veys K, Casteels I (2019) Ophthalmic outcome in a Belgian cohort of cystinosis patients treated with a compounded preparation of cysteamine eye drops: retrospective analysis

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STEP 4 (Rubino et al., JAMA 2021) addressed the maintenance question: after 20 weeks of semaglutide run-in (during which participants lost a mean of 10.6% of body weight), those randomized to continue semaglutide for 48 more weeks lost an additional 7.9%, while those switched to placebo regained 6.9%

Keratin forms a scaly plug that blocks the opening of the hair follicle