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Biological Functions The cytosolic enzyme nicotinamide N-methyltransferase (NNMT) has been newly discovered to modulate the levels of nicotinamide precursors required for NAD+ biosynthesis and thus plays a crucial role in regulating the NAD+ salvage pathway and cellular metabolism

Vitamin B12 (cobalamin) is a water-soluble vitamin crucial for: DNA synthesis Energy metabolism Red blood cell production Neurological function Its naturally found in animal products like meat, eggs, dairy, and fish

Here is a more specific review of those issues