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The trial is led by two Chief Investigators, Professor Philip Newsome at Kings College London and Arun Sanyal at the VCU School of Medicine, United States, and funded by Novo Nordisk

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Jul 16 2021;10(7)doi:10.3390/cells10071805

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However, in A Diabetes Outcome Progression Trial (ADOPT), metformin exhibited a reduced risk of monotherapy failure compared with the sulfonylurea glibenclamide (known as glyburide in the USA and Canada) and slower rate of loss of beta cell function, although it was inferior to the thiazolidinedione rosiglitazone [20]