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Defensive displays vary: common responses include flattening the neck/body, S-shaped striking posture, repeated strikes, and vigorous thrashing

Another assumption is that a malfunction of the hypothalamicpituitaryadrenal (HPA) axis, which also contributes to the pathophysiology of depression, leads to upregulation of vitamin D receptor expression in these areas and increased vitamin D activity due to the presence of the enzyme 1-alpha-hydroxylase

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Proven treatments, including retinal photocoagulation (PRP), VEGF inhibitors, and corticosteroids, have demonstrated efficacy in both clinical trials and real-world applications [37]

Zhou Q, Wang Y, Lu Z, Wang B, Li L, You M, et al