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3.2 Semaglutide vs dulaglutide 3.2.1 Study characteristics In this section, four studies were thoroughly examined, all of which were RCT studies

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While we adjusted for baseline comorbidities, granular detailssuch as insulin resistance levels, socioeconomic factors, and prediabetes status (ICD-10 R73.03)could not be consistently ascertained

Pharmacokinetics (How Long They Last): Semaglutide: Half-life: Approximately 7 days Reaches steady state: After 4-5 weeks Duration of action: Remains active for one week between doses Time to peak concentration: 1-3 days after injection Tirzepatide: Half-life: Approximately 5 days Reaches steady state: After 4 weeks Duration of action: Remains active for one week between doses Time to peak concentration: 8-72 hours after injection Both medications are designed for once-weekly dosing and maintain therapeutic levels throughout the week