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New blood vessel formation brings oxygen, nutrients, and immune cells to injured tissues

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Additionally, for samples that underwent the same pre-exposure treatment, those exposed to a combination of zinc and ciprofloxacin saw delayed ciprofloxacin resistance compared to those exposed to only ciprofloxacin resulting in up to a 5 lower MIC within the first 2 days of antibiotic exposure

These effects were dependent on UBE3As ligase activity and were observed both with and without oncogene expression, indicating an endogenous role for UBE3A in clock regulation

These data show a statistically significant inverse correlation (Supplementary Fig