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This origin is what places MOTS-c in a separate research category from hGH-fragment or GHRH-analog compounds, since its activity is rooted in mitochondrial biology rather than the pituitary-hormone axis

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Tripeptide in human plasma that prolongs survival of normal liver cells and stimulates growth in neoplastic liver. Nature New Biology , 243(124), 8587

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doi:10.1002/14651858.CD004326

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