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Barcoded universal forward 515F primers and 806R reverse primers containing Illumina adapter sequences, which target the highly conserved V4 region, were used to amplify microbial DNA ( 16S rRNA gene sequencing produced 2,610,204 reads with a median of 50,609 per sample (range: 9,512 470,848)

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Long-Acting Formulation: Its extended duration of action allows for less frequent dosing, enhancing patient adherence