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Methionine, a sulfur-containing, essential amino acid, is a precursor of S-adenosylmethionine, a cofactor for one-carbon metabolism and the final methyl donor for the methylation of DNA, RNA, proteins, and phospholipids.The methionine synthase plays a paramount role in the synthesis of nitrogenous bases (purines and pyrimidines) involved in the formation of DNA

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Therefore, Research established roles for ERR, ERR, and ERR in mitochondrial gene expression, oxidative metabolism, cardiac energetics, and exercise adaptation

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biology and engineering must both weigh in