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Studies in primary endothelial cells grown in culture, as well as in animal models illustrate that a deficiency of GPx1 alters endothelial dependent vasodilation by regulating bioavailable nitric oxide [39, 60, 61, 70, 71]

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revealed that in aqueous media, chicken erythrocyte histone H5 is mostly disordered (it is essentially in the form of a flexible random coil) but the N-terminal part of this protein gains globular helical structure in the presence of salts (Crane-Robinson et al., 1976)

The structure of this stable gastric pentadecapeptide consists of 15 amino acids, and looks a little something like this: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val