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Nrf2 is a master transcription factor that plays a key role in regulating the expression of antioxidant proteins that protect the body from oxidative damage and inflammation
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In other words, through the foods you consume and the supplements you use, you can, to some degree, improve the instructions that come from your genes for body function
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Future studies should prioritize (1) isolating and characterizing the active compounds within these botanicals, (2) elucidating their precise molecular targets (e.g., thyroid peroxidase, sodium-iodide symporter, cytokine signaling pathways), and (3) conducting well-designed controlled clinical trials to rigorously evaluate their safety and efficacy in human patients
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