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This intracellular conversion has been confirmed pharmacokinetically: in a peer-reviewed human bioavailability crossover trial, SAG was undetectable in plasma following oral administration because rapid deacetylation occurs before or immediately upon systemic entry meaning the entire SAG load is converted to GSH before reaching blood circulation

Studies have shown that it can reduce the expression of pro-inflammatory cytokines such as Tumour Necrosis Factor-alpha (TNF-) and Interleukin-6 (IL-6)

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