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New results released this week from the SURMOUNT-5 clinical trial comparing tirzepatide (Zepbound) to semaglutide (Wegovy) are closely aligned to Truveta Researchs GLP-1 comparative effectiveness study, initially shared more than a year ago on November 27, 2023 and published earlier this year in JAMA Internal Medicine

Majzoub A, ElBardisi H, Covarrubias S, et al

451,452 Together, these abnormalities destabilize immune tolerance and promote lupus nephritis, immune complex deposition, and tissue injury

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Promoting GLP-1s is therefore an obvious strategic focus for management