Therefore, through the above-mentioned ways of regulating the microbiota-metabolism axis, GLPs restore carbohydrate metabolism, augment insulin responsiveness, reduce inflammation, reduction in blood sugar levels, and restore gut barrier function ( In previous studies, it has been found that there is a series of interactions among the microbiome within mouth, intestines, pancreas, together with lungs, which makes the occurrence and development of intestinal diseases ( In conclusion, GLPs significantly improve insulin resistance, reduce inflammation, and lower blood glucose levels by fostering helpful bacteria proliferation while hindering detrimental microorganisms, and reshaping the balance of the microbiota and metabolic homeostasis, thus opening up new avenues for studying the mechanisms of blood glucose reduction ( 6 Innovations in combination therapy, structure, and dosage forms Combination therapy has become a key approach in modern medicine to tackle complex diseases and improve treatment success rates, thanks to its advantages such as synergistic effects, reduced drug resistance, alleviated side effects, and multi-target intervention
Int J Pediatric Otorhinolaryngol
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