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The medication's formulation is slightly alkaline compared to the skin's natural pH, which may cause transient irritation of subcutaneous tissues and nerve endings

Patient adherence to dosing recommendations and lifestyle modifications can substantially impact how quickly tolerance develops and symptoms resolve

This also means that tens of thousands of SUD patients currently receiving treatment are already receiving both GLP-1 and indicated SUD treatments, establishing an important track record of safe monotherapy and combination use of GLP-1 in these populations

Symptoms may include swelling of the face, mouth, and throat, difficulty breathing, a rapid resting heartbeat, and feeling faint