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H 2 O, Milli-Q, and IS: Kynurenine-D6 and Tryptophan-D8 were obtained from Sigma-Aldrich (St

Discussion High Pyroglutamic acid indicates a disturbed GSH homeostasis in symptomatic TTR-V30M gene carriers In a recent study, we demonstrated that the formation of the aggregation-prone NNTTR species, initially discovered in plasma from TTR-V30M gene carriers [21], is promoted by the formation of a disulfide bridge [22]