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I think if you are somebody who has severe obesity or has struggled with this all their life, I feel like most of those folks are probably either on a GLP-1 or on the path to it because the success level is so clear

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Repeated cycles of sickling and unsickling shortens the lifespan of the damaged sickle RBCs to about 1/6th that of normal RBCs ( FIGURE 2 These events trigger a cascade of pro-inflammatory activity setting off multiple pathophysiological factors that also involve neutrophils, platelets, and vascular endothelium (Sundd et al., 2019)

For someone already managing acid reflux or sulfur burps from their GLP-1 medication, this non-fermentable property is not just convenient

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