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These results are roughly in line with what Lilly has demonstrated for tirzepatide (22.5% and 20.9% respectively at 72 weeks), but fall short of the 25% bar for efficacy many investors were anticipating, BMO Capital Markets analysts wrote in a note to investors

The question is not whether these benefits exist

Porokhovnik LN, cape BM, yaeo A, Chudakova YuM, Ershova ES, Veiko NN, Gorbachevskaya NL, Mamokhina U, Sorokin A, Basova AY, Lapshin MS, Izhevskaya VL, Kostyuk SV (2023) Association of NEF2L2 Rs35652124 polymorphism with Nrf2 induction and genotoxic stress biomarkers in autism