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[52] gave diet-induced obesity (DIO) mice daily GLP-1R/Gcg receptor (GcgR) double agonist (cotadutide), Lira, Gcg agonist (g1437), and Lira+g1437 respectively

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The increase in melanin results in a darker, tanned appearance, similar to the effect of sun exposure but without harmful solar UV radiation, thus why the Melanotropic Peptide is often dubbed a sunless tanning agent

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