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However, if the intracellular concentration exceeds maximum metabolic capacity (saturates the enzyme) drug levels within the cell remain high, so reducing uptake (reduced concentration gradient) and ER

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Results Maintaining the stability of the degenerative IVD with fibroblast injection therapy Using a needle puncture IVD degeneration model in rats, 16 we assessed the therapeutic effect of the autologous injection of DFbs into the NP 1, 2, and 3 months postsurgery

Safety concerns: Nanomaterials may induce inflammation or oxidative stress, necessitating thorough toxicity evaluations and a deeper understanding of nanomaterial-biological interactions

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