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477 SGLT2 inhibitors include canagliflozin, dapagliflozin, and empagliflozin that have been approved by the FDA for combined use with diet and exercise to lower blood sugar and excessive insulin secretion in adults with type 2 diabetes
Additionally, recent studies have highlighted the regulatory role of STING in antifungal immunity: STING deficiency enhances the antifungal immune response during systemic C
HIF-1 has been shown to enhance the expression of fatty acid synthase (FASN), which catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA (113)
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