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Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors

It acts by modulating apoptosis, autophagy, oxidative stress, and inflammatory responses through key signaling pathways

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Several approaches evaluated the inhibition of TGF- signaling in glioma (www.clinicaltrials.gov) using antibodies, antisense oligonucleotides, ligand traps or TGF- receptor kinase inhibitors 29,45

J Genet Eng Biotechnol 20:14