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Gene Set Enrichment Analysis (GSEA), as implemented in the R/Bioconductor package clusterProfiler (v 4.4.4), was used to search for modulated pathways of WikiPathways database ( Mutation profiles, comprising SNV and CNV (amplifications and homozygous deletions) and their frequencies, for the KEAP1 , NRF2 and CUL3 genes were downloaded from cBioportal for all 28 studies forming the TCGA PanCancer dataset

Overall, the plant extract exerts significant vasodilatory, vasoprotective, and free radical-scavenging effects ( White and red ginger demonstrated notable ACEI activity in rats and also showed anti-HC effects due to this ACEI activity

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10.1073/pnas.0504251102 234 WilkinsonS

Cell 153 , 21627 (2013)