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In vitro research has shown that a clove extract has insulin-like effects on liver cells, inhibiting the breakdown of stored carbohydrates into glucose and preventing a subsequent rise in levels of circulating glucose (Prasad 2005

treatment with methylene blue), as demonstrated by a lack of enhanced PPP rate in cells when hexokinase is inhibited [109], and patients with hexokinase deficiency exhibit nonspherocytic hemolytic anemia [110]

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