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www.nhs.uk/conditions/vitamin-b12-or-folate-deficiency-anaemia/causes/ National Institutes of Health (2018)

A study using immunofluorescent staining confirmed that ketamine treatment resulted in increased expression levels of glucose transporter 3 (GLUT3) and phosphorylated ERK1/2 (P-ERK1/2) in astrocytes, but not in neurons, within the prefrontal cortex and suggested that ketamine enhances glucose metabolism in the prefrontal cortex through the nuclear localization of P-ERK1/2 in astrocytes, which promotes the expression of GLUT3 (Ouyang et al., 2021)

Additionally, the plasticity of macrophages, which allows them to switch phenotypes in response to environmental changes, poses a challenge for therapeutic interventions aimed at reprogramming them

In preclinical models, wound closure is 30 to 40% faster with GHK-Cu than with controls