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Some people report positive results with other treatments, but those with true pernicious anemia are unlikely to benefit at all

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Two realities now coexist: (i) unprecedented demand, and (ii) supply strain not just on drug substance, but also on delivery systems (pens, autoinjectors, fill-finish). He further stresses that, Device capacity is a real bottleneck: pen bodies, springs, needles, cartridges, and aseptic fillfinish all sit on long lead times and specialized lines

Cancer Research , 83 , 237286