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Treatment should be discontinued if pancreatitis is suspected

However, it should be emphasized that these drugs are not sulfonamides and do not cross-react in individuals with sulfonamide allergies

Metabolic Changes: The metabolic benefits (e.g., improved insulin sensitivity) may diminish, potentially increasing the risk of weight-related health issues

This can alter alcohols addictive potential as the pharmacokinetics of a substance is known to influence intake 44,45,46,47,48,49,50