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In a model of idiopathic ASD, BTBR mice, selective positive allosteric modulation of GABA-A receptors containing 2/3 subunits with compound 2261 at a minimum effective dose of 0.3 mg/kg improved social behavior, although it did not affect repetitive self-grooming

Fellow actor Michael J

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Knijnenburg TA, Wang L , Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Research Network CGA, Monnat RJ, Xiao Y, Wang C

Ergnzt durch 400 mg NAC und 100 mg Alpha-Liponsure fr eine umfassende Versorgung