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doi: 10.3389/fphar.2026.1767206 Received 14 December 2025 Revised 01 June 2026 Accepted 08 June 2026 Published 30 June 2026 Volume 17 - 2026 Edited by Nidhi Jalan-Sakrikar, Mayo Clinic, United States Reviewed by Slaan Pavlovi, University of Belgrade, Serbia Uro akar, University of Belgrade, Serbia Seddik Hammad, Heidelberg University, Germany Updates Copyright 2026 Philips, Sreemohan, Baby, Theruvath, Oommen, Ahamed, Tharakan and Augustine

At the same time, isoflavones suppressed NF-B, NOS, and COX-2, as well as the pro-inflammatory cytokine release (e.g., TNF-, IL-6, and IL-1) in the hippocampus of sleep-deprived mice

How hormones affect the brain Hormones do more than just control physiologic processes like metabolism, growth, and reproduction

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