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Safety Considerations and Patient Selection GLP-1 agonists are contraindicated in personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2
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Of adults receiving combination cagrilintide and semaglutide, 71.4% lost at least 10% of their body weight and 53.6% achieved a 15% or higher weight loss at 32 weeks
A 2024 clinical trial in chronic rhinosinusitis failed, highlighting the risks associated with indication expansion
doi: 10.1371/journal.pntd.0005118 50 WalshC
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