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Informed by recent studies from 2024-2025, future research should prioritize the development of disease-specific ferroptosis biomarkers, optimization of combination therapy regimens, creation of next-generation modulators with enhanced cell-type specificity and pharmacokinetic properties, and elucidation of ferroptosis crosstalk with other regulated cell death pathways (152)

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Standard berberine is poorly absorbed & less than 1% of what you swallow actually makes it into your bloodstream in an active form