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On the genetic side, research by Heun and Maier (1993) showed that BP-II may be genetically different from BP-I and unipolar depression

Furthermore, large-scale, multicenter clinical trials are necessary to establish efficacy benchmarks and personalized delivery protocols

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Each PCR reaction was prepared using cDNA derived from 1000 ng of total RNA, SYBR Green PCR master mix, and specific primers targeting -actin, DNMT1, or DNMT3

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