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Consistently, regardless of the initial positions of palmitate either located in the membrane as seen in the cryo-EM structure or placed outside of the membrane, our MD simulations found that the -carboxylate spacer stably inserted into the TM1-TM2 cleft and the 16-carbon palmitic chain is deeply buried in the receptor-lipid interface, contributing multiple strong contacts to stabilize the complexes (Supplementary Fig

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Az egyik kzs pont, amit minden autoimmun betegsgben szenved betegemnl megfigyeltem, a kompromittlt blrendszeri egszsg

Taken together, the zinc exporter SLC30A1 modulated cadmium toxicity by regulating intracellular zinc levels, which in turn induced protective effects, such as the up-regulation of metallothioneins (Fig 4I)

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