In addition to energy production, ketones support whole-body physiology and are signalling molecules that serve as ligands for G protein coupled receptors and modifiers of gene expression by regulating DNA post-translational modifications
The complaint lays out the science behind the allegation: tirzepatide is a large peptide molecule that digestive enzymes destroy before it can reach the bloodstream
As a compounding pharmacist, I find this encouraging because it shows there's active discussion around therapies that many patients and providers have been asking about
Appl Microbiol Biotechnol 106(23):79177931 Liu L et al (2022) Functional comparison of Clostridium butyricum and sodium butyrate supplementation on growth, intestinal health, and the anti-inflammatory response of broilers
This aligns with clinical outcomes Reductions in myocardial infarction, stroke, and cardiovascular mortality in outcome trials likely reflect pleiotropic cardiometabolic protection, not just weight loss