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J Mol Biol 323(2):387 Sesti G, Avogaro A, Belcastro S, Bonora BM, Croci M, Daniele G, Dauriz M, Dotta F, Formichi C, Frontoni S, Invitti C, Orsi E, Picconi F, Resi V, Bonora E, Purrello F (2019) Ten years of experience with DPP-4 inhibitors for the treatment of type 2 diabetes mellitus

3 Absorption-Related DDIs Changes in gastric pH Chelation or complex formation Altered GI motility Example: Calcium reducing absorption of certain antibiotics

These non-incretin metabolic peptides frequently exert effects on peripheral tissues such as skeletal muscle, adipose tissue, liver, and vasculature, and often engage receptors distinct from those targeted by current therapies

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Dynamics in anemia development and dysregulation of iron homeostasis in hospitalized patients with COVID-19