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Description

Cryogenic electron microscopy (cryoEM) structural analyses revealed that E27 replaces endogenous CRL4 substrate receptors, resulting in proper positioning of STAT2 for polyubiquitylation and subsequent proteasomal destruction to inhibit host IFN signalling

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Thus, E

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The column was equilibrated with acetonitrile/ammonium formate, pH 2.5 (2/98)

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[PubMed] Cohen ED, Miller RF

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