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These findings may help explain historical interest in pain and withdrawal research, but they do not establish an opioid-like clinical effect in people

PMC 1039326

Myouga F, Hosoda C, Umezawa T, Iizumi H, Kuromori T, Motohashi R, et al

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Research (primarily in animal models) has shown potential effects such as: Supporting soft tissue repair (muscle, tendon, ligament) Promoting angiogenesis (formation of new blood vessels) Supporting gastrointestinal integrity and mucosal protection Modulating inflammatory responses While these findings are promising, clinical research in humans remains limited, and results should be interpreted with caution