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Circulating GLP-1 is rapidly inactivated by the serum protease dipeptidyl peptidase-4 (DPP-IV), which removes the two N -terminal amino acids 26 , and neprilysin

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Novo Nordisk asks FDA not to allow GLP-1 compounding Novo Nordisk has filed another Citizen's Petition with the FDA seeking to block compounding pharmacies in the US from making versions of one of its GLP-1 agonist drugs