retatrutide gip glp-1 glucagon receptor agonist Glucagon-like peptide-1 receptor: mechanisms and advances in therapy GLP-3 (R) - Triple GIP

doi: 10.1056/NEJMoa2032183 52 WaddenTABaileyTSBillingsLKDaviesMFriasJPKorolevaAet al

They are prepared by licensed pharmacies based on individual prescriptions, but they have not undergone the same regulatory review as brand-name drugs like Ozempic or Wegovy

So here are the big areas that we have to care about first

Prescription GLP-1 receptor agonists are medicines that have been studied in clinical trials for specific uses, such as type 2 diabetes and chronic weight management in selected patients

A review of 29 studies of patients that underwent bariatric surgery showed a significant improvement in liver function tests and a meta-analysis reported a decrease in steatosis, inflammation, and fibrosis [9, 10]