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Probiotic products have weaker evidence for constipation specifically, but emerging research shows certain strains (particularly Akkermansia muciniphila) may support the gut bacteria that enhance GLP-1 activity

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Their resting metabolic rate remained higher, which means they retained more of their calorie-burning capacity even as total body weight decreased

This is particularly relevant if you are using a compounded tirzepatide formulation where dose adjustments are more flexible

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