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We then monitor IGF-1 levels at regular intervals typically at 6 weeks, 3 months, and every 36 months thereafter to confirm the protocol is working and adjust dosing as needed

Manufacturers of creatine monohydrate often use a one size fits all approach in their recommended dose, which is generally much more than even very heavy athletes need

However, IGF-1 was shown to be an important growth-related hormone that has a GH-independent growth stimulating effects that in some cases acts synergistically with GH (172)

Users with metabolic syndrome or insulin resistance often see the earliest improvements