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Patients experiencing significant cold intolerance should undergo thyroid function testing, complete blood count to assess for anemia (including iron studies), vitamin B12 levels (especially if taking metformin), and metabolic panel to evaluate overall health status

Dipeptidyl peptidase-4 inhibition in patients with type 2 diabetes treated with saxagliptin, sitagliptin, or vildagliptin

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Key Takeaways Fat pad loss: Rapid weight loss from GLP-1 drugs can reduce natural fat pads in feet, causing pain and discomfort Prevention is crucial: Maintaining protein intake and resistance training helps preserve muscle and fat pad integrity Professional care helps: Early podiatric intervention can prevent complications and provide effective pain management Diabetic considerations: Patients with type 2 diabetes face additional risks including foot ulcers and neuropathy Treatment options exist: Custom orthotics, padding, and targeted therapies can restore foot comfort and function Understanding Ozempic Feet: The Medical Reality The term Ozempic feet describes foot-related complications that can occur when someone loses weight rapidly while taking GLP-1 medications such as Ozempic, Wegovy, or other similar drugs