Research shows that vitamin B12 has a half-life of 6 days in the blood, making it six days before the administered amount gets excreted from your body
Further research is needed with aging, fit, healthy subjects, measuring a variety of physiologic and metabolic endpoints to determine if the results of this case study prevail, and if so, the mechanism of any such benefits achieved

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10.3389/fnut.2020.00023 38
For example, the HRV 3C protease recognizes and cleaves the sequence Leu-Glu-Val-Leu-Phe-Gln--Gly-Pro, enabling the separation of the GST tag from the target protein