doi: 10.1016/j.cmet.2018.12.023 103 GuoXLiuFDengJDaiPQinYLiZet al
The understanding of this mechanism was later derived from a separate study involving mice.
These findings suggest that AST protects dopaminergic neurons through suppression of ER stress and stabilization of the miR-7/SNCA regulatory loop, presenting a promising target for PD therapy ( In summary, AST demonstrates promising therapeutic potential in PD by targeting key pathological mechanisms such as oxidative stress, neuroinflammation, and mitochondrial dysfunction
*Correspondence: Mariola Herbet, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Quick Tip : If youre new to glutathione supplementation and have no urgent medical needs, start with high-quality liposomal oral glutathione at 500-1000 mg daily for 4 weeks to assess your response before considering the higher cost and risks of IV therapy
