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Blood sugar remains stable, appetite stays controlled, fat mobilization increases, and muscle protein synthesis continues despite reduced caloric intake

This review will use the term MASLD, defined as the presence of hepatic steatosis with no other discernible cause, in conjunction with at least one cardiometabolic risk factor (CMRF), such as type 2 diabetes mellitus (T2DM), obesity, hypertension, or dyslipidemia

Objective markers include fasting IGF-1 testing, though most users don't have access to frequent bloodwork during cessation