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Therefore, it is tempting to speculate that the effects of these compounds are, in part, an expression of their ability to quench the toxic effect of ROS

All mice used in this study had CAG repeats in the range of 148153, with corresponding base pairs of 500550, as determined by PCR

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References Cao S, Zhao Z, Zheng Y et al (2022) A library of ROS-catalytic metalloenzyme mimics with atomic metal centers

Determining the appropriate dosage of cagrlintide when used alongside tirzepatide requires careful consideration of individual patient factors, including tolerance, response, and any side effects