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Here's what peer-reviewed research says about how your microbiome and the fiber that feeds it support its natural production

If accelerated advancement causes intolerable symptoms, simply extend your current dose duration or step down to a previous dose before trying again

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However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist

stopping: Instead of stopping abruptly, some providers may recommend gradually reducing the dose to help manage the return of hunger and support a smoother transition