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These receptors are present in brain regions that regulate appetite, energy, and sleep-wake cycles

Author Contributions Jos Luis Grriz provided expert clinical opinion and critical revision of the manuscript for important intellectual content and has helped establish the structure and contents of the manuscript

Furthermore, advancements in formulation technologies, such as the application of nanocarriers and sustained-release and controlled-release technologies, may enhance the bioavailability and efficacy of BPC 157, providing more possibilities for its clinical application