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Nigral degeneration correlates with persistent activation of cerebellar Purkinje cells in MPTP-treated monkeys

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It promotes the expression of FSP1, reduces cellular level of Fe 2+ , ferritin heavy chain, and MDA, increases GPX4, and GSH, inhibits lipid peroxidation and cell ferroptosis, enhances the vitality of renal tubular cells, and alleviates AKI in septic rats (179)